CSU was established in April 2000 by merging the former Hunan Medical University (HMU), the former Changsha Railway University (CRU) and the former Central South University of Technology (CSUT). The predecessor of CSUT was Central South Institute of Mining and Metallurgy founded in 1952 and that of CRU was Central South College of Civil Engineering and Architecture founded in 1953.
CSU has complete disciplinary systems for Non-ferrous Metals, Medicine, Rail Transit, etc., covering Philosophy, Economics, Law, Education, Literature, Science, Engineering, Medicine, Management and Art, and Military Science was embraced. At present, it has 6 national key primary disciplines, 12 national key secondary disciplines, 1 national key discipline (in development) and 61 national key clinical specialties, and sets up 31 schools and institutes with 104 undergraduate majors, 35 primary disciplines authorized for the doctoral degree, 46 primary disciplines authorized for the master’s degree, 2 doctoral degree categories, 23 master's degree categories and 32 post-doctoral research centers.
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